Department of Neuroscience

Students and Postdocs - Publications and Postions

 

Grad Student/Post-Doc Selected First Author Publications since 1995:

Landmesser Lab

Stoeckli, E., Sonderreger, P., Pollerberg, G.E., and Landmesser, L. (1997) Interference with axonin-1 and NrCAM interactions unmasks a floor plate activity inhibitory for commissural axons. Neuron 18: 209-221.

Stoeckli, E. and Landmesser, L. (1998) Axon guidance at choice points. Curr. Opinion Neurobiology 8: 73-79.

Milner, L., and Landmesser, L. (1999) Cholinergic and GABAergic inputs drive patterend spontaneous motoneuron activity prior to target contact. J. Neurosci. 19: 3007-3022

Usiak, Marianne and Landmesser, L. (1999) Neuromuscular activity blockade by muscimol and dTC differentially affects survival of embryonic chick motoneurons. J. Neurosci. 19: 7925-7939

Rafuse, V. , Polo-Parada, L., and Landmesser, L. (2000) Structural and functional alterations of neuromuscular junctions in NCAM- deficient mice . J. Neurosci.20:6529-6539.

Deneris Lab

Hendricks, T.*, Francis, N*., Fyodorov, D. and Deneris, E. (1999) The ETS Domain Factor Pet-1 is an Early and Precise Marker of Central 5-HT Neurons and Interacts with a Conserved Element in Serotonergic Genes. J. Neurosci. 19: 10348-10356.

Fyodorov, D., Nelson, T., and Deneris, E. (1998) Pet-1, a novel ETS domain factor that can activate neuronal nAchR gene transcription. J. Neurobiol. 34: 151-163.

McDonough, J. and Deneris, E. (1997) b43': an enhancer displaying neural-restricted activity is located in the 3'-untranslated exon of the rat nicotinic acetylcholine receptor b4 gene.J. Neurosci., 17: 2273-2283.

Yang, X., Yang, F., Fyodorov, D., Wang, F. McDonough, J., Herrup, K., and Deneris, E. (1997) Elements between the protein coding regions of the adjacent b4 and a3 acetylcholine receptor genes direct neuron-specific expression in the CNS. J. Neurobiol. 32: 311-324.

Fyodorov, D. and Deneris, E. (1996) The POU domain of SCIP/Tst-1/Oct-6 is sufficient for activation of an acetylcholine receptor promoter. Mol. Cell. Biol. 16: 5004-5014.

Friel Lab

Albrecht, M.A., Colegrove, S.L., Friel, D.D. (2002) Differential regulation of endoplasmic reticulum (ER) Ca2+ uptake and release rates accounts for multiple modes of Ca2+-induced Ca2+ release. J. Gen. Physiol. 119:211-33.

Albrecht, M.A., Colegrove, S.L., Hongpaisan, J., Pivovarova, N.B., Andrews, S.B., Friel, D.D. (2001) Multiple modes of calcium-induced calcium release in sympathetic neurons I: Attenuation of endoplasmic reticulum Ca2+ accumulation at low [Ca2+]i during weak stimulation. J. Gen. Physiol. 118: 83-100.

Colegrove, S.L., Albrecht, M.A. Friel, D.D. (2000). Dissection of mitochondrial Ca2+ uptake and release fluxes in situ following depolarization-evoked [Ca2+]i elevations in sympathetic neurons. J. Gen. Physiol. 115: 351-369. For this and the following manuscript, See Commentary: Mitochondrial memory banks - Calcium stores keep a record of neuronal stimulation J. Gen. Physiol. 115: 347-350.

Colegrove, S.L., Albrecht, M.A. Friel, D.D. (2000). Quantitative analysis of mitochondrial Ca2+ uptake and release pathways in sympathetic neurons: reconstruction of the recovery following depolarization-evoked [Ca2+]i elevations. J. Gen. Physiol. 115: 371-388.

Hall Lab

Memberg, S.P. and A.K. Hall (1995), Dividing neuron precursors express neuron specific tubulin. Journal of Neurobiology 27: 26-43.

Memberg, S.P. and A.K. Hall. (1995), Proliferation, differentiation and survival of rat sensory neuron precursors in vitro are selectively regulated by trophic factors. Molecular and Cellular Neuroscience 6: 323-336.

Shirley, M., Campbell, J.D. and A.K. Hall (1996), Sympathetic neuronal precursors express a neuronal trait before a catecholamine synthetic enzyme in vivo. Journal of Neuroscience Research 46: 42-48.

Ai, X., MacPhedran, S.E. and A.K. Hall. (1998) Depolarization stimulates initial calcitonin gene-related peptide expression by embryonic sensory neurons in vitro. Journal of Neuroscience  18: 9294-9302.

Ai, X., Cappuzzello, J. A. K. Hall. (1999) Activin and bone morphogenetic proteins induce calcitonin gene-related peptide in embryonic sensory neurons in vitro. Molecular and Cellular Neuroscience 14: 506-518.

Herrup Lab

Yang, Y., Geldmacher, D.S. and Herrup, K. 2001. DNA replication precedes neuronal cell death in Alzheimer's disease. J. Neurosci., in press.

Zwingman, T.A., Neumann, P.E., Noebels, J.L. and Herrup, K. 2001. Rocker is a new variant of the voltage dependent calcium channel gene Cacna1a. J. Neurosci., in press.

Maricich, S.M. and Herrup, K., 1999. Pax-2 expression defines a subset of GABAergic interneurons and their precursors in the developing murine cerebellum. J. Neurobiol. 41:281-294.

Gilmore, E.C., Ohshima, T. Goffinet, A.M., Kulkarni, A.B. and Herrup, K 1998. Cyclin dependent kinase 5 deficient mice demonstrate novel developmental arrest in cerebral cortex. J. Neurosci., 18:6370-6377.

Walther, E., Dichgans, M., Maricich, S.M., Romito, R.R. Yang, F., Dziennis, S., Zackson, S., Hawkes, R. and Herrup, K. 1998. Genomic sequences of aldolase C (Zebrin II) direct lacZ expression exclusively in non-neuronal cells. Proc. Nat. Acad. Sci. 95:2615-2620.

Katz Lab

Erickson, J. T., C. Mayer, A., Jawa, L. Ling, E. B. Olson Jr, G. S. Mitchell and D.M. Katz (1998). Chemoafferent degeneration and carotid body hypoplasia following chronic hyperoxia in newborn rats, J. Physiology (Lond.), 509:519-526.

Balkowiec, A. and D.M. Katz (1998). Brain-derived neurotrophic factor is required for normal development of the central respiratory rhythm in mice, J. Physiol. (Lond.), 510: 527-533.

Balkowiec, A., D. Kunze and D.M. Katz (2000). Brain-derived neurotrophic factor acutely inhibits AMPA currents in developing sensory relay neurons, J. Neuroscience, 20:1094-1911.

Balkowiec, A. and D.M.Katz. Activity-dependent release of endogenous brain-derived neurotrophic factor from primary sensory neurons detected by ELISA in situ, J. Neuroscience, 20: 7417-7423.

Erickson, J.T., Brosenitsch, T. and D.M. Katz. Brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor are required simultaneously for survival of dopaminergic primary sensory neurons in vivo, J. Neuroscience, in press.

Landreth Lab

McDonald, D., Brunden, K. and Landreth, G. (1997), Beta-amyloid Fibrils Activate Tyrosine Kinase-dependent Signaling and Superoxide Production by Microglia. J. Neurosci. 17:2284-2294

McDonald, D., Bamberger, M and Landreth, G. Beta-amyloid fibrils activate parallel MAP kinase pathways in microglia and THP-1 monocytes. J. Neurosci. 18:4451-4460 , 1998.

Swanson, K., Taylor, L., Haung, L., Burlingame, A. and Landreth, G. Transcription factor phosphorylation by pp90rsk2: Identification of Fos kinase and NGFI-B kinase I as pp90rsk2. J. Biol. Chem. 273:19965-19971, 1999.

Moeslein, F., Myers, M. and G. Landreth. The CLK family kinases, CLK1 and CLK2, phosphorylate and activate the tyrosine phosphatase, PTP1B. J. Biol. Chem. 274:26697-26704, 1999.

Menegay, H., Moeslein, M. and Landreth, G. The dual specificity protein kinase CLK3 is abundantly expressed in mature mouse spermatozoa. Exp. Cell Res. 253:463-473, 1999.

Bamberger, M. and Landreth, G. Microglial Interaction with b-amyloid-Implications for the pathogenesis of Alzheimer's Disease. Microsc. Res. Tech. In Press, 2001

Lemmon Lab

Burden-Gulley, S.M., Payne, H.R., Lemmon, V. (1995) Growth cones are actively influenced by substrate-bound adhesion molecules. J. Neurosci., 15:4370-4381

Wong, E.V., Kenwrick, S., Willems, P., Lemmon, V. (1995) Mutations in the cell adhesion molecule L1 cause mental retardation. Trends in Neuroscience, 18:168-172

Kamiguchi, H., Long, K.E., Pendergast, M., Schaefer, A.W., Rapoport, I, Kirchhausen, T., Lemmon, V. (1998) The neural cell adhesion molecule L1 interacts with the AP-2 adaptor and is endocytosed via the clathrin-mediated pathway. J. Neurosci. 18:5311-5321

Schaefer, A.W., Kamei, Y, Kamiguchi, H., Wong, E.V., Rapoport, I., Kirchhausen, T., Beach, C.M., Landreth, G., Lemmon, S.K., and Lemmon, V. L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1 J. Cell Biol. 157: 1223-1232, 2002

Long, K.E., Asou, H., Snider, M.D., Lemmon, V., (2001) The role of endocytosis in regulating L1 mediate adhesion. J. Biol. Chem, 276: p. 1285-1290

De Angelis, E, Brümmendorf, T, Cheng, L, Lemmon, V, and Kenwrick, S. Alternative Use of a Mini Exon of the L1 Gene Affects L1 Binding to Neural Ligands, J. Biol. Chem., 276 :32738-32742, 2001, J. Biol. Chem., 276 :32738-32742.

Roth Lab

MS Choudhary, AZ Uluer, N Sachs, RA Glennon, RB Westkaemper and BL Roth (1995), Differential ergoline and ergopeptine binding to 5-hydroxytryptamine2A receptors: ergolines require an aromatic residue at position 340 for high affinity binding. Mol Pharmacol., 47: 450-457.

E-P Palvimaki, BL Roth, H Majasuo, A Laakso, M Kuoppamaki, E Syvlahti and J Hietala. (1996), Interactions of selective serotonin reuptake inhibitors with the serotonin 5-HT2C receptor. Psychopharmacol, 126: 234-240.

SA Berry, M Shah, N Khan and BL Roth. (1996), Rapid agonist induced internalization of 5-Hyroxytryptamine2A (5-HT2A) receptors occurs via endosomes in vitro. Mol Pharmacol, 50: 306-313.

DA Willins, AY Deutsch and BL Roth. (1997), 5-HT2A receptors are localized on pyramidal neurons and interneurons in rat cortex. Synapse, 27:79-82.

Silver Lab

McKeon, R.J., Hoke, A. and Silver, J. (1995) Injury induced proteoglycans inhibit the potential for laminin mediated axon growth on astrocytic scars. Exp. Neurol., 136:32-43.

Canning, D.R., Hoke, A., Malemud, C.J. and Silver, J. (1996) A potent inhibitor of neurite outgrowth that predominates in the extracellular matrix of reactive astrocytes Int. J. Dev. Neurosci. Bignami Memorial Issue. 14:153-176.

Davies, J.A., Fitch, M.T., Memberg, S.P., Hall, A.K., Raisman, G. and Silver, J. (1997) Regeneration of adult axons in white matter tracts of the central nervous system. Nature 390:680-683.

DeWitt, D. A., Doller, C., Perry, G. and Silver, J. (1998) Astrocytes regulate microglial phagocytosis of senile plaque cores of Alzheimer's disease. Exp. Neurol., 149:329-340.

Fitch, M.T., Doller, C., Combs, C.K., Landreth, G.E. , and Silver, J. (1999) Cellular and molecular mechanisms of glial scarring and progressive cavitation: In vivo and in vitro analysis of inflammation induced secondary injury following central nervous system trauma. J. Neurosci. 19:8182-8198.

 

Job Placement for Graduate Students/Post-Docs:

Landmesser Lab

Sheryl Scott, Professor, Dept. of Neuroscience, Univ. of Utah

Marcia Honig, Assoc. Prof., Dept. of Anatomy & Neurobio., Univ. of TN

Michael Vogel, Assoc. Prof., Dept. of Psychiatry, Univ. of Maryland

Lisa Dahm, Res. Assoc., Beckman Research Inst., City of Hope, CA

Fabiana Kupke, Res. Assoc., University of Maryland

Cynthia Lance-Jones, Assoc. Prof., Dept. of Neurobio. & Anatomy, Univ. of Pittsburgh, S.O.M.

Michael O'Donovan, Sr. Scientist, National Inst. of Neurological Disorders and Stroke

Kathryn Tosney, Prof., Div. of Biological Sciences, Univ. of Michigan

Hideaki Tanaka, Prof., Dept. of Pharmacology, Gunma Univ., Japan

Barbara Fredette, Research Assoc., LaJolla Cancer Research Inst., CA

Esther Stoeckli, Asst. Prof. University of Basel, Switzerland

Victor Rafuse, Assist. Professor of Pharmacology, Dalhousie University, Nova Scotia, Canada

Deneris Lab

Xiangdong Yang, Resident, University Hosptials, Cleveland, OH

Nicole Francis, Ph.D.,Damon Runyon Walter Winchell Fellow.Postdoctoral Fellow, R. Kingston, Harvard

Dmitry Fyodorov, Ph.D., Postdoctoral Fellow, J. Kadonaga, UC San Diego

Jennifer McDonough, Ph.D., Postdoctoral fellow, Cleveland Clinic Foundation, Laboratory of Bruce Trapp, Department of Neurosciences.

Friel Lab

Meredith Albrecht, MD.,Ph.D. is a resident in anesthesiology at Massachusetts General in Boston

Hall Lab

Stacey Memberg MD., Ph.D., pediatrician in private practice

Sally MacPhedran M.S., is now a fourth year medical student at CWRU SOM.

Melissa Shirley M.S., Ohio public secondary school teacher Olentangy High School, OH

Xingbin Ai, Ph.D., Postdoc in lab of Dr. Charles Emerson, U. Penn.

Herrup Lab

Richard Wetts, Staff Scientist, City of Hope

Michael Vogel, Associate Professor, Maryland Psychiatric Institute, University of Maryland

Kevin Kelley, Associate Professor, Mt. Sinai Medical School (NYC)

Ernst Walther, Assistant Professor, Neurologische Klinik und Institut für klinische Neuroimmunologie

Martin Dichgans, Assistant Professor, Neurologische Klinik und Institut für klinische Neuroimmunologie

Edward Gilmore, MD/PhD, 4th year medical student at CWRU

Stephen Maricich, MD/PhD, 1st year Pediatrics resident at Rainbow Babies and Children's

Barbara Kuemerle, Postdoctoral, CARU

Katz Lab

Guoping Fan, post-doctoral fellow, Whitehead Institute, MIT, Cambridge, MA.

James C.W. Finley, MD, PhD., Assoc. Professor of Medicine, CWRU.

Catherine D. Thaler, PhD., post-doctoral fellow,Dept. Biology, University of California at Riverside

Torbjorn Hertzberg, MD, PhD., Asst. Professor Pediatrics, Karolinska Hospital, Stockholm, Sweden.

Jeffrey Erickson, PhD, Instructor, Department of Biology, CWRU

Landreth Lab

Linda M. Roy, Ph.D., Hughes Postdoctoral, Fellow, Dept. of Pharmacology, University of Colorado Health, Science Center, Denver.

Carolyn Schanen, M.D./Ph.D., Assistan Professor of Genetics, University of California, Los Angeles School of Medicine

Jeffrey Twiss, M/D./ Ph. D., Assistant Professor of Pathology, UCLA School of Medicine, Los Angeles, CA.

Lori K. Taylor, Ph.D. Post-Doc Fellow (with Dr. Ray Erikson) Harvard University.

Michael P. Myers, Ph.D.Postdoctoral Fellow (with Dr. Nick Tonks) Cold Spring Harbor Laboratories

Andre E. Nel M.D./Ph.D., Professor of Medicine and Clinical Immunology, UCLA School of Medicine, Los Angeles, CA.

Nadine Goodman, Ph.D., Science Instructor, Gilmore Academy. Gates Mills, OH.

Lemmon Lab

Judy Drazba, Director Imaging Facilities, Cleveland Clinic Research foundation

Susan Burden-Gulley, Instructor, Dept. of Molecular Biology and Micro Biology, CWRU

Eric Wong, Assistant Professor, Univ. of Louisville

Andy Schaefer, Post-doc, Yale Univ., Paul Forescher lab

Krisitn Long, Medical Student, CWRU

H.K. Kamiguchi, Sr Scientist, RIKEN, Japan

Roth Lab

Raye Z. Litten, PhD--Physiologist, National Institute of Alcoholism and Alcohol Abuse

John Mehegan MD--Assistant Professor, Department of Medicine, University of Iowa Medical School.

Joseph Carcillo MD--Assistant Professor, Department of Pediatrics, University of Pittsburgh Medical School.

Eugenia Legan MD--Senior Medical Consultant, Searle, Chicago, IL

Sy H. Fatemi MD, PhD--Associate Professor, Department of Psychiatry, University of Minnesota Medical School.

Esa-Pekka Palvimaki MD, University of Turko, Finland. Naseem Khan, PhD--staff scientist, Alpha Diagnostics, Inc (Houston, Tx)

Edward Hyde, PhD, Astra Pharmaceuticals, Brisbane

Silver Lab

Mark Hankin, Associate Professor, University of Toledo

John Rudge, Senior Research Associate, Regeneron Pharmaceutical Co.

George Smith, Endowed Professor, Department of Physiology, University of Kentucky

Ahment Hoke, Assistant Professor, Department of Neurology, Johns Hopkins University

Diane Snow, Assistant Professor, Department of Anatomy and Neurobiology, University of Kentucky

Robert McKeon, Assistant Professor, Department of Anatomy and Cell Biology, Emory University

Stephen Davies, Assistant Professor, Departments of Anatomy and Neurosurgery, Baylor College of Medicine

David DeWitt, Assistant Professor, Liberty University

Zigmond Lab

Robert Mohney, Ph.D., Postdoctoral Fellow,Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, N.C.

Yi Sun, Ph.D.Postdoctoral Fellow, Division of Neuroscience, Children's Hospital, Boston, MA

 

Updated Feb. 21, 2001

© 1995-2001

Department Neurosciences

School of Medicine

Case Western Reserve University.

All rights reserved.